Cook Pasta: Start by bringing a large pot of salted water to a boil. Once boiling, add the elbow macaroni and cook until al dente, usually about 8-10 minutes. Drain and set aside to keep warm.

Make Cheese Sauce: In a saucepan, melt the unsalted butter over medium heat. Whisk in the all-purpose flour and let it cook for about 1 minute until slightly bubbly. Slowly pour in the whole milk, whisking continuously until the mixture thickens, around 3-5 minutes.

Add Cheeses: Lower the heat and stir in the sharp cheddar, Monterey Jack, and Parmesan cheeses. Mix until the cheese is completely melted and the sauce is smooth. Season with salt and pepper to taste.

Combine: Carefully fold the cooked macaroni into the creamy cheese sauce, ensuring each noodle is well-coated and enveloped in that luscious mixture.

Prepare for Baking: Preheat your oven to 350°F (175°C). Transfer the cheesy pasta mixture into a greased baking dish. Evenly sprinkle the buttered panko breadcrumbs on top for that perfect crunch.

Bake: Place the dish in the preheated oven and bake uncovered for 25-30 minutes or until the top is golden brown and the edges are bubbly. Let it cool for a few minutes before serving to let the flavors meld together.